MHA508 Phoenix Radio Technologists in Texas Tennesee and South Carolina PPT Hi, Please read carefully the attachments, and for this topic you are going to

MHA508 Phoenix Radio Technologists in Texas Tennesee and South Carolina PPT Hi, Please read carefully the attachments, and for this topic you are going to have valuable sources and is in APA format. Also, do not plagiarize or use another bad sources such as course hero website. Citation book is Skloot, R. (2011). The immortal life of Henrietta Lacks. New York: Broadway Paperbacks. Skloot, Rebecca – The Immortal Life Of
Henrietta Lacks
The Immortal life of Henrietta Lacks
EARLY PRAISE FOR
The IMMORTAL LIFE of HENRIETTA LACKS
“Skloot makes a remarkable debut with this multilayered story about ‘faith, science, journalism, and grace.’”
—PUBLISHERS WEEKLY (starred review)
“Heartbreaking and powerful, Rebecca Skloot’s sensitive account tells of the enduring,
deeply personal sacrifice of this African American woman and her family and, at long last, restores a human face to the cell line that propelled 20th-century biomedicine. A stunning illustration of how race, gender, and disease intersect to produce a unique form of social vulnerability, this is a poignant, necessary, and brilliant book.”
—ALONDRA NELSON, Columbia University; editor of Technicolor: Race, Technology and
Everyday Life
“The Immortal Life of Henrietta Lacks
takes the reader on a remarkable journey—compassionate, troubling, funny, smart, and irresistible. Along the way, Rebecca Skloot will change the way you see medical science and
lead you to wonder who we should value more—the researcher or the research subject? Ethically fascinating and completely engaging—I couldn’t recommend it more.”
—DEBORAH BLUM, author of The Poisoner’s Handbook
“This is a science biography like the world has never seen … Ladies and gentlemen, meet
Henrietta Lacks. Chances are, at the level of your DNA, your inoculations, your physical
health and microscopic well-being, you’ve already been introduced.”
—MELISSA FAY GREENE, author of Praying for Sheetrock and There Is No Me Without
You
“Remarkable … The portrayal of Lacks’s full life makes the story come alive with her humanity and the palpable relationship between race, science, and exploitation.”
—PAULA J. GIDDINGS, author of Ida, a Sword Among Lions; Elizabeth A. Woodson 1922
Professor, Afro-American Studies, Smith College
“This book is extraordinary. As a writer and a human being, Skloot stands way, way out
there ahead of the pack.”
—MARY ROACH, author of Stiff and Bonk
The Immortal life of Henrietta Lacks
The Immortal life of Henrietta Lacks
For my family:
My parents, Betsy and Floyd; their spouses, Terry and Beverly;
my brother and sister-in-law, Matt and Renee;
and my wonderful nephews, Nick and Justin.
They all did without me for far too long because of this book,
but never stopped believing in it, or me.
And in loving memory of my grandfather,
James Robert Lee (1912–2003),
who treasured books more than anyone I’ve known.
The Immortal life of Henrietta Lacks
Contents
A Few Words About This Book
Prologue: The Woman in the Photograph
Deborah’s Voice
Part One
LIFE
1. The Exam … 1951
2. Clover … 1920–1942
3. Diagnosis and Treatment … 1951
4. The Birth of HeLa … 1951
5. “Blackness Be Spreadin All Inside” … 1951
6. “Lady’s on the Phone” … 1999
7. The Death and Life of Cell Culture … 1951
8. “A Miserable Specimen” … 1951
9. Turner Station … 1999
10. The Other Side of the Tracks … 1999
11. “The Devil of Pain Itself” … 1951
Part Two
DEATH
12. The Storm … 1951
13. The HeLa Factory … 1951–1953
14. Helen Lane … 1953–1954
15. “Too Young to Remember” … 1951–1965
16. “Spending Eternity in the Same Place” … 1999
17. Illegal, Immoral, and Deplorable … 1954–1966
18. “Strangest Hybrid” … 1960–1966
19. “The Most Critical Time on This Earth Is Now” … 1966–1973
20. The HeLa Bomb … 1966
21. Night Doctors … 2000
22. “The Fame She So Richly Deserves” … 1970–1973
Part Three
IMMORTALITY
23. “It’s Alive” … 1973–1974
24. “Least They Can Do” … 1975
25. “Who Told You You Could Sell My Spleen?” … 1976–1988
26. Breach of Privacy … 1980–1985
Photo Insert
27. The Secret of Immortality … 1984–1995
28. After London … 1996–1999
29. A Village of Henriettas … 2000
30. Zakariyya … 2000
31. Hela, Goddess of Death … 2000–2001
32. “All That’s My Mother” … 2001
33. The Hospital for the Negro Insane … 2001
34. The Medical Records … 2001
35. Soul Cleansing … 2001
36. Heavenly Bodies … 2001
37. “Nothing to Be Scared About” … 2001
38. The Long Road to Clover … 2009
Where They Are Now
Afterword
Acknowledgments
Notes
The Immortal life of Henrietta Lacks
A Few Words About This Book
T
his is a work of nonfiction. No names have been changed, no characters invented, no events
fabricated. While writing this book, I conducted more than a thousand hours of interviews with
family and friends of Henrietta Lacks, as well as with lawyers, ethicists, scientists, and journalists who’ve written about the Lacks family. I also relied on extensive archival photos and documents, scientific and historical research, and the personal journals of Henrietta’s daughter,
Deborah Lacks.
I’ve done my best to capture the language with which each person spoke and wrote: dialogue appears in native dialects; passages from diaries and other personal writings are
quoted exactly as written. As one of Henrietta’s relatives said to me, “If you pretty up how
people spoke and change the things they said, that’s dishonest. It’s taking away their lives,
their experiences, and their selves.” In many places I’ve adopted the words interviewees used
to describe their worlds and experiences. In doing so, I’ve used the language of their times
and backgrounds, including words such as colored. Members of the Lacks family often referred to Johns Hopkins as “John Hopkin,” and I’ve kept their usage when they’re speaking.
Anything written in the first person in Deborah Lacks’s voice is a quote of her speaking, edited
for length and occasionally clarity.
Since Henrietta Lacks died decades before I began writing this book, I relied on interviews, legal documents, and her medical records to re-create scenes from her life. In those
scenes, dialogue is either deduced from the written record or quoted verbatim as it was recounted to me in an interview. Whenever possible I conducted multiple interviews with multiple sources to ensure accuracy. The extract from Henrietta’s medical record in chapter 1 is a
summary of many disparate notations.
The word HeLa, used to refer to the cells grown from Henrietta Lacks’s cervix, occurs
throughout the book. It is pronounced hee-lah.
About chronology: Dates for scientific research refer to when the research was conducted,
not when it was published. In some cases those dates are approximate because there is no
record of exact start dates. Also, because I move back and forth between multiple stories, and
scientific discoveries occur over many years, there are places in the book where, for the sake
of clarity, I describe scientific discoveries sequentially, even though they took place during the
same general period of time.
The history of Henrietta Lacks and the HeLa cells raises important issues regarding science, ethics, race, and class; I’ve done my best to present them clearly within the narrative of
the Lacks story, and I’ve included an afterword addressing the current legal and ethical debate surrounding tissue ownership and research. There is much more to say on all the issues,
but that is beyond the scope of this book, so I will leave it for scholars and experts in the field
to address. I hope readers will forgive any omissions.
The Immortal life of Henrietta Lacks
We must not see any person as an abstraction.
Instead, we must see in every person a universe with its own secrets,
with its own treasures, with its own sources of anguish,
and with some measure of triumph.
—ELIE WIESEL
from The Nazi Doctors and the Nuremberg Code
The Immortal life of Henrietta Lacks
PROLOGUE
The Woman in the Photograph
T
here’s a photo on my wall of a woman I’ve never met, its left corner torn and patched together with tape. She looks straight into the camera and smiles, hands on hips, dress suit neatly
pressed, lips painted deep red. It’s the late 1940s and she hasn’t yet reached the age of thirty.
Her light brown skin is smooth, her eyes still young and playful, oblivious to the tumor growing
inside her—a tumor that would leave her five children motherless and change the future of
medicine. Beneath the photo, a caption says her name is “Henrietta Lacks, Helen Lane or
Helen Larson.”
No one knows who took that picture, but it’s appeared hundreds of times in magazines
and science textbooks, on blogs and laboratory walls. She’s usually identified as Helen Lane,
but often she has no name at all. She’s simply called HeLa, the code name given to the
world’s first immortal human cells—her cells, cut from her cervix just months before she died.
Her real name is Henrietta Lacks.
I’ve spent years staring at that photo, wondering what kind of life she led, what happened
to her children, and what she’d think about cells from her cervix living on forever—bought,
sold, packaged, and shipped by the trillions to laboratories around the world. I’ve tried to imagine how she’d feel knowing that her cells went up in the first space missions to see what
would happen to human cells in zero gravity, or that they helped with some of the most important advances in medicine: the polio vaccine, chemotherapy, cloning, gene mapping, in
vitro fertilization. I’m pretty sure that she—like most of us—would be shocked to hear that
there are trillions more of her cells growing in laboratories now than there ever were in her
body.
There’s no way of knowing exactly how many of Henrietta’s cells are alive today. One scientist estimates that if you could pile all HeLa cells ever grown onto a scale, they’d weigh
more than 50 million metric tons—an inconceivable number, given that an individual cell
weighs almost nothing. Another scientist calculated that if you could lay all HeLa cells ever
grown end-to-end, they’d wrap around the Earth at least three times, spanning more than 350
million feet. In her prime, Henrietta herself stood only a bit over five feet tall.
I first learned about HeLa cells and the woman behind them in 1988, thirty-seven years
after her death, when I was sixteen and sitting in a community college biology class. My instructor, Donald Defler, a gnomish balding man, paced at the front of the lecture hall and
flipped on an overhead projector. He pointed to two diagrams that appeared on the wall be-
hind him. They were schematics of the cell reproduction cycle, but to me they just looked like
a neon-colored mess of arrows, squares, and circles with words I didn’t understand, like “MPF
Triggering a Chain Reaction of Protein Activations.”
I was a kid who’d failed freshman year at the regular public high school because she never showed up. I’d transferred to an alternative school that offered dream studies instead of
biology, so I was taking Defler’s class for high-school credit, which meant that I was sitting in
a college lecture hall at sixteen with words like mitosis and kinase inhibitors flying around. I
was completely lost.
“Do we have to memorize everything on those diagrams?” one student yelled.
Yes, Defler said, we had to memorize the diagrams, and yes, they’d be on the test, but that
didn’t matter right then. What he wanted us to understand was that cells are amazing things:
There are about one hundred trillion of them in our bodies, each so small that several thousand could fit on the period at the end of this sentence. They make up all our tissues—muscle, bone, blood—which in turn make up our organs.
Under the microscope, a cell looks a lot like a fried egg: It has a white (the cytoplasm)
that’s full of water and proteins to keep it fed, and a yolk (the nucleus) that holds all the genetic information that makes you you. The cytoplasm buzzes like a New York City street. It’s
crammed full of molecules and vessels endlessly shuttling enzymes and sugars from one part
of the cell to another, pumping water, nutrients, and oxygen in and out of the cell. All the
while, little cytoplasmic factories work 24/7, cranking out sugars, fats, proteins, and energy to
keep the whole thing running and feed the nucleus. The nucleus is the brains of the operation;
inside every nucleus within each cell in your body, there’s an identical copy of your entire genome. That genome tells cells when to grow and divide and makes sure they do their jobs,
whether that’s controlling your heartbeat or helping your brain understand the words on this
page.
Defler paced the front of the classroom telling us how mitosis—the process of cell division—makes it possible for embryos to grow into babies, and for our bodies to create new
cells for healing wounds or replenishing blood we’ve lost. It was beautiful, he said, like a perfectly choreographed dance.
All it takes is one small mistake anywhere in the division process for cells to start growing
out of control, he told us. Just one enzyme misfiring, just one wrong protein activation, and
you could have cancer. Mitosis goes haywire, which is how it spreads.
“We learned that by studying cancer cells in culture,” Defler said. He grinned and spun to
face the board, where he wrote two words in enormous print: HENRIETTA LACKS.
Henrietta died in 1951 from a vicious case of cervical cancer, he told us. But before she
died, a surgeon took samples of her tumor and put them in a petri dish. Scientists had been
trying to keep human cells alive in culture for decades, but they all eventually died. Henrietta’s
were different: they reproduced an entire generation every twenty-four hours, and they never
stopped. They became the first immortal human cells ever grown in a laboratory.
“Henrietta’s cells have now been living outside her body far longer than they ever lived inside it,” Defler said. If we went to almost any cell culture lab in the world and opened its freezers, he told us, we’d probably find millions—if not billions—of Henrietta’s cells in small vials on
ice.
Her cells were part of research into the genes that cause cancer and those that suppress
it; they helped develop drugs for treating herpes, leukemia, influenza, hemophilia, and Parkinson’s disease; and they’ve been used to study lactose digestion, sexually transmitted diseases, appendicitis, human longevity, mosquito mating, and the negative cellular effects of
working in sewers. Their chromosomes and proteins have been studied with such detail and
precision that scientists know their every quirk. Like guinea pigs and mice, Henrietta’s cells
have become the standard laboratory workhorse.
“HeLa cells were one of the most important things that happened to medicine in the last
hundred years,” Defler said.
Then, matter-of-factly, almost as an afterthought, he said, “She was a black woman.” He
erased her name in one fast swipe and blew the chalk from his hands. Class was over.
As the other students filed out of the room, I sat thinking, That’s it? That’s all we get?
There has to be more to the story.
I followed Defler to his office.
“Where was she from?” I asked. “Did she know how important her cells were? Did she
have any children?”
“I wish I could tell you,” he said, “but no one knows anything about her.”
After class, I ran home and threw myself onto my bed with my biology textbook. I looked
up “cell culture” in the index, and there she was, a small parenthetical:
In culture, cancer cells can go on dividing indefinitely, if they have a continual supply of
nutrients, and thus are said to be “immortal.” A striking example is a cell line that has been reproducing in culture since 1951. (Cells of this line are called HeLa cells because their original
source was a tumor removed from a woman named Henrietta Lacks.)
That was it. I looked up HeLa in my parents’ encyclopedia, then my dictionary: No Henrietta.
As I graduated from high school and worked my way through college toward a biology degree, HeLa cells were omnipresent. I heard about them in histology, neurology, pathology; I
used them in experiments on how neighboring cells communicate. But after Mr. Defler, no
one mentioned Henrietta.
When I got my first computer in the mid-nineties and started using the Internet, I searched
for information about her, but found only confused snippets: most sites said her name was
Helen Lane; some said she died in the thirties; others said the forties, fifties, or even sixties.
Some said ovarian cancer killed her, others said breast or cervical cancer.
Eventually I tracked down a few magazine articles about her from the seventies. Ebony
quoted Henrietta’s husband saying, “All I remember is that she had this disease, and right
after she died they called me in the office wanting to get my permission to take a sample of
some kind. I decided not to let them.” Jet said the family was angry—angry that Henrietta’s
cells were being sold for twenty-five dollars a vial, and angry that articles had been published
about the cells without their knowledge. It said, “Pounding in the back of their heads was a
gnawing feeling that science and the press had taken advantage of them.”
The articles all ran photos of Henrietta’s family: her oldest son sitting at his dining room table in Baltimore, looking at a genetics textbook. Her middle son in military uniform, smiling
and holding a baby. But one picture stood out more than any other: in it, Henrietta’s daughter,
Deborah Lacks, is surrounded by family, everyone smiling, arms around each other, eyes
bright and excited. Except Deborah. She stands in the foreground looking alone, almost as if
someone pasted her into the photo after the fact. She’s twenty-six years old and beautiful,
with short brown hair and catlike eyes. But those eyes glare at the camera, hard and serious.
The caption said the family had found out just a few months earlier that Henrietta’s cells were
still alive, yet at that point she’d been dead for twenty-five years.
All of the stories mentioned that scientists had begun doing research on Henrietta’s children, but the Lackses didn’t seem to know what that research was for. They said they were
being tested to see if they had the cancer that killed Henrietta, but according to the reporters,
scientists were studying the Lacks family to learn more about Henrietta’s cells. The stories
quoted her son Lawrence, who wanted to know if the immortality of his mother’s cells meant
that he might live forever too. But one member of the family remained voiceless: Henrietta’s
daughter, Deborah.
As I worked my way through graduate school studying writing, I became fixated on the
idea of someday telling Henrietta’s story. At one point I even called directory assistance in
Baltimore looking for Henrietta’s husband, David Lacks, but he wasn’t listed. I had the idea
that I’d write a book that was a biography of both the cells and the woman they came
from—someone’s daughter, wife, and mother.
I couldn’t have imagined it then, but that phone call would mark the beginning of a decadelong adventure through scientific laboratories, hospitals, and mental institutions, with a
cast of characters that would include Nobel laureates, grocery store clerks, convicted felons,
and a professional con artist. While trying to make sense of the history of cell culture and the
complicated ethical debate surrounding the use of human tissues in research, I’d be accused
of conspiracy and slammed into a wall both physically and metaphorically, and I’d eventually
find myself on the receiving end of something that looked a lot like an exorcism. I did eventually meet Deborah, who would turn out to be one of the strongest and most resilient women
I’d ever known. We’d form a deep personal bond, and slowly, without realizing it, I’d become a
character in her story, and she in mine.
Deborah and I came from very different cultures: I grew up white and …
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